Michael G. Rosenfeld

加州大学圣地亚哥分校医学杰出教授
生物科学部兼职教授
美国国家科学院院士
美国艺术与科学院院士
美国科学促进协会会员
美国霍华德休斯医学研究院研究员

Research Summary

Michael Rosenfeld investigates the molecular and architectural strategies responsible for integrating genome-wide transcriptional responses to diverse signaling systems, critical for physiological and behavioral processes in all vertebrates. His work has uncovered unexpected roles of enhancers as transcription units, global roles of noncoding RNAs, and regulated dynamic alterations in nuclear architecture. These enhancer-based strategies link regulated gene responses to other cellular response programs/machinery, including DNA damage/repair and inflammation, and suggest new approaches to several prevalent diseases. 

http://biology.ucsd.edu/research/faculty/mrosenfeld

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